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JPH2 Antibody

CAT: 0223-57-048Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-048Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.
NCBI Gene ID
57158
Swiss Prot
Q9BR39
Accession Number
Q9BR39
Host
Rabbit
Reactivity
Human
Immunogen
This JPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-643 amino acids from the C-terminal region of human JPH2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
JPH2
NCBI Official Name
Junctophilin-2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Woo, J.S., et al. Biochem. J. 427 (1) :125-134 (2010)
Background Reference 03
Yamazaki, D., et al. Pharmacol. Ther. 121 (3) :265-272 (2009)
Background Reference 04
Landstrom, A.P., et al. J. Mol. Cell. Cardiol. 42 (6) :1026-1035 (2007)
Other Product Names
Junctophilin-2, JP-2, Junctophilin type 2, JPH2, JP2
Tested Applications
WB
Protein ID
27805486
Physical Properties
Liquid

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