RPL34 Antibody

• Background:

  Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Transcript variants derived from alternative splicing, alternative transcription initiation sites, and/or alternative polyadenylation exist; these variants encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

• NCBI Gene ID:

  6164

• Swiss Prot:

  P49207

• Accession Number:

  P49207

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  This RPL34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human RPL34.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  13 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RPL34

• NCBI Official Name:

  60S ribosomal protein L34

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)

• Background Reference 02:

  Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

• Background Reference 03:

  Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

• Background Reference 04:

  Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :

• Other Product Names:

  60S ribosomal protein L34, RPL34

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid