NIP1 Antibody

• Background:

  NIP1 (BNIP1) is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. Alternative splicing of this gene results in four products of unknown function. Transcript variant BNIP1 contains the entire coding region of the gene. This variant contains a fully conserved BH3 domain, which has been associated with pro-apoptotic function.

• NCBI Gene ID:

  662

• Swiss Prot:

  Q12981

• Accession Number:

  Q12981

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This NIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-127 amino acids from human NIP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  BNIP1

• NCBI Official Name:

  Vesicle transport protein SEC20

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang, H., et al., FEBS Lett. 448 (1) :23-27 (1999) .

• Background Reference 02:

  Boyd, J.M., et al., Cell 79 (2) :341-351 (1994) .

• Other Product Names:

  Vesicle transport protein SEC20, BCL2/adenovirus E1B 19 kDa protein-interacting protein 1, Transformation-related gene 8 protein, TRG-8, BNIP1, NIP1, SEC20L

• Tested Applications:

  WB, IHC-P

• Protein ID:

  93141310

• Physical Properties:

  Liquid