ANKRD6 Antibody

• Background:

  ANKRD6 recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals (By similarity) .

• NCBI Gene ID:

  22881

• Swiss Prot:

  Q9Y2G4

• Accession Number:

  Q9Y2G4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ANKRD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human ANKRD6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  80 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ANKRD6

• NCBI Official Name:

  Ankyrin repeat domain-containing protein 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Haribaskar, R., et al. Biochem. Biophys. Res. Commun. 387 (1) :212-217 (2009)

• Background Reference 02:

  Miyasaka, K.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (27) :11274-11279 (2007)

• Background Reference 03:

  Schwarz-Romond, T., et al. Genes Dev. 16 (16) :2073-2084 (2002)

• Background Reference 04:

  Tissir, F., et al. Dev. Dyn. 224 (4) :465-469 (2002)

• Other Product Names:

  Ankyrin repeat domain-containing protein 6, Diversin, ANKRD6, KIAA0957

• Tested Applications:

  WB, IHC-P

• Protein ID:

  327478595

• Physical Properties:

  Liquid