ANKRD6 Antibody

• Background :

  ANKRD6 recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals (By similarity) .

• NCBI Gene ID :

  22881

• Swiss Prot :

  Q9Y2G4

• Accession Number :

  Q9Y2G4

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ANKRD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human ANKRD6.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  80 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ANKRD6

• NCBI Official Name :

  Ankyrin repeat domain-containing protein 6

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Haribaskar, R., et al. Biochem. Biophys. Res. Commun. 387 (1) :212-217 (2009)

• Background Reference 02 :

  Miyasaka, K.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (27) :11274-11279 (2007)

• Background Reference 03 :

  Schwarz-Romond, T., et al. Genes Dev. 16 (16) :2073-2084 (2002)

• Background Reference 04 :

  Tissir, F., et al. Dev. Dyn. 224 (4) :465-469 (2002)

• Other Product Names :

  Ankyrin repeat domain-containing protein 6, Diversin, ANKRD6, KIAA0957

• Tested Applications :

  WB, IHC-P

• Protein ID :

  327478595

• Physical Properties :

  Liquid