ARHGAP22 Antibody

• Background :

  ARHGAPs, such as ARHGAP22, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]) .

• NCBI Gene ID :

  58504

• Swiss Prot :

  Q7Z5H3

• Accession Number :

  Q7Z5H3

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-633 amino acids from the C-terminal region of human ARHGAP22.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  77 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  ARHGAP22

• NCBI Official Name :

  Rho GTPase-activating protein 22

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02 :

  Dick, D.M., et al. Mol. Psychiatry (2010) In press :

• Background Reference 03 :

  Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

• Background Reference 04 :

  Katoh, M., et al. Int. J. Mol. Med. 14 (2) :333-338 (2004)

• Other Product Names :

  Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22, ARHGAP22, RHOGAP2

• Tested Applications :

  WB

• Protein ID :

  74750129

• Physical Properties :

  Liquid