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RPS12 Antibody

CAT: 0223-56-764Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-764Size:400 µL
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Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
NCBI Gene ID
6206
Swiss Prot
P25398
Accession Number
P25398
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This RPS12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human RPS12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Pig, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
15 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RPS12
NCBI Official Name
40S ribosomal protein S12
NCBI Organism
Homo sapiens
Background Reference 01
Yu, Y., et al. Protein Sci. 14 (6) :1438-1446 (2005)
Background Reference 02
Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)
Background Reference 03
Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :
Background Reference 04
Sampath, P., et al. Mol. Cell. Biol. 23 (5) :1509-1519 (2003)
Other Product Names
40S ribosomal protein S12, RPS12
Tested Applications
WB
Protein ID
224471878
Physical Properties
Liquid

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