RAB11B Antibody

• Background:

  The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]) .[supplied by OMIM].

• NCBI Gene ID:

  9230

• Swiss Prot:

  Q15907

• Accession Number:

  Q15907

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  This RAB11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human RAB11B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  24 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RAB11B

• NCBI Official Name:

  Ras-related protein Rab-11B

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Agop-Nersesian, C., et al. PLoS Pathog. (7), E1001029 (2010) :

• Background Reference 02:

  Silvis, M.R., et al. Mol. Biol. Cell 20 (8) :2337-2350 (2009)

• Background Reference 03:

  Kathiresan, S., et al. Nat. Genet. 41 (1) :56-65 (2009)

• Background Reference 04:

  Scapin, S.M., et al. J. Struct. Biol. 154 (3) :260-268 (2006)

• Other Product Names:

  Ras-related protein Rab-11B, GTP-binding protein YPT3, RAB11B, YPT3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  38258938

• Physical Properties:

  Liquid