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PAX6 Antibody

CAT: 0223-56-734Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-734Size:400 µL
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Background
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].
NCBI Gene ID
5080
Swiss Prot
P26367
Accession Number
P26367
Host
Rabbit
Reactivity
Human
Immunogen
This PAX6 antibody is generated from rabbits immunized with a recombinant protein from human PAX6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
PAX6
NCBI Official Name
Paired box protein Pax-6
NCBI Organism
Homo sapiens
Background Reference 01
Gosmain, Y., et al. J. Biol. Chem. 285 (43) :33381-33393 (2010)
Background Reference 02
Vuzman, D., et al. Biophys. J. 99 (4) :1202-1211 (2010)
Background Reference 03
Zhang, X., et al. Cell Stem Cell 7 (1) :90-100 (2010)
Background Reference 04
Bremond-Gignac, D., et al. Mol. Vis. 16, 1705-1711 (2010) :
Other Product Names
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
Tested Applications
WB, IHC-P, IF
Protein ID
6174889
Physical Properties
Liquid

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