SLC8A3 Antibody

• Background:

  This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.

• NCBI Gene ID:

  6547

• Swiss Prot:

  P57103

• Accession Number:

  P57103

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SLC8A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 585-614 amino acids from the C-terminal region of human SLC8A3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  103 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SLC8A3

• NCBI Official Name:

  Sodium/calcium exchanger 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Pulina, M.V., et al. J. Biol. Chem. 281 (28) :19645-19654 (2006)

• Background Reference 03:

  Gomez-Villafuertes, R., et al. J. Neurosci. 25 (47) :10822-10830 (2005)

• Background Reference 04:

  Lindgren, R.M., et al. Gene 348, 143-155 (2005) :

• Other Product Names:

  Sodium/calcium exchanger 3, Na (+) /Ca (2+) -exchange protein 3, Solute carrier family 8 member 3, SLC8A3, NCX3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  34395973

• Physical Properties:

  Liquid