SLC8A3 Antibody

CAT: 0223-56-660Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-660Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
NCBI Gene ID
6547
Swiss Prot
P57103
Accession Number
P57103
Host
Rabbit
Reactivity
Human
Immunogen
This SLC8A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 585-614 amino acids from the C-terminal region of human SLC8A3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
103 kDa
Fragment
Rabbit Ig
Symbol
SLC8A3
NCBI Official Name
Sodium/calcium exchanger 3
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Pulina, M.V., et al. J. Biol. Chem. 281 (28) :19645-19654 (2006)
Background Reference 03
Gomez-Villafuertes, R., et al. J. Neurosci. 25 (47) :10822-10830 (2005)
Background Reference 04
Lindgren, R.M., et al. Gene 348, 143-155 (2005) :
Other Product Names
Sodium/calcium exchanger 3, Na (+) /Ca (2+) -exchange protein 3, Solute carrier family 8 member 3, SLC8A3, NCX3
Tested Applications
WB, IHC-P
Protein ID
34395973
Physical Properties
Liquid

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