DNAJB6 Antibody

CAT: 0223-56-462Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-462Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
NCBI Gene ID
10049
Swiss Prot
O75190
Accession Number
O75190
Host
Rabbit
Reactivity
Human
Immunogen
This DNAJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the Central region of human DNAJB6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Symbol
DNAJB6
NCBI Official Name
DnaJ homolog subfamily B member 6
NCBI Organism
Homo sapiens
Background Reference 01
Mitra, A., et al. J. Biol. Chem. 285 (32) :24686-24694 (2010)
Background Reference 02
Edo De Bock, C., et al. Int. J. Oncol. 36 (5) :1155-1163 (2010)
Background Reference 03
Hageman, J., et al. Mol. Cell 37 (3) :355-369 (2010)
Background Reference 04
Lowe, J.K., et al. PLoS Genet. (2), E1000365 (2009) :
Other Product Names
DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, HSJ-2, MRJ, MSJ-1, DNAJB6, HSJ2, MRJ, MSJ1
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid

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