TRIM69 Antibody

• Background :

  This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. It may play a role in apoptosis (By similarity) .

• NCBI Gene ID :

  140691

• Swiss Prot :

  Q86WT6

• Accession Number :

  Q86WT6

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  This TRIM69 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the N-terminal region of human TRIM69.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  57 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  TRIM69

• NCBI Official Name :

  E3 ubiquitin-protein ligase TRIM69

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

• Background Reference 02 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03 :

  Shyu, H.W., et al. Exp. Cell Res. 287 (2) :301-313 (2003)

• Background Reference 04 :

  Shyu, H.W., et al. Mech. Dev. 108 (1-2), 213-216 (2001) :

• Other Product Names :

  E3 ubiquitin-protein ligase TRIM69, 632-, RFP-like domain-containing protein trimless, RING finger protein 36, Tripartite motif-containing protein 69, TRIM69, RNF36

• Tested Applications :

  WB, IHC-P

• Protein ID :

  229462760

• Physical Properties :

  Liquid