CHRND Antibody

• Background:

  The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

• NCBI Gene ID:

  1144

• Swiss Prot:

  Q07001

• Accession Number:

  Q07001

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CHRND antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the Central region of human CHRND.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  59 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CHRND

• NCBI Official Name:

  Acetylcholine receptor subunit delta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Saccone, N.L., et al. Genes Brain Behav. 9 (7) :741-750 (2010)

• Background Reference 02:

  Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)

• Background Reference 03:

  Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :

• Background Reference 04:

  Saccone, N.L., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (4), 453-466 (2009) :

• Other Product Names:

  Acetylcholine receptor subunit delta, CHRND, ACHRD

• Tested Applications:

  WB, Flow

• Protein ID:

  543759

• Physical Properties:

  Liquid