SOX3 Antibody

• Background:

  This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.

• NCBI Gene ID:

  6658

• Swiss Prot:

  P41225

• Accession Number:

  P41225

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-196 amino acids from the Central region of human SOX3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SOX3

• NCBI Official Name:

  Transcription factor SOX-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dateki, S., et al. J. Clin. Endocrinol. Metab. 95 (8) :4043-4047 (2010)

• Background Reference 02:

  Sato, Y., et al. Mol. Cell. Biochem. 337 (1-2), 267-275 (2010) :

• Background Reference 03:

  Mojsin, M., et al. Biochem. J. 425 (1) :107-116 (2010)

• Background Reference 04:

  Bleyl, S.B., et al. Am. J. Med. Genet.143A (23), 2785-2795 (2007) :

• Other Product Names:

  Transcription factor SOX-3, SOX3

• Tested Applications:

  WB

• Protein ID:

  48429228

• Physical Properties:

  Liquid