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IGF2 Antibody

CAT: 0223-55-712Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-55-712Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
3481
Swiss Prot
P01344
Accession Number
P01344
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This IGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the Central region of human IGF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Symbol
IGF2
NCBI Official Name
Insulin-like growth factor II
NCBI Organism
Homo sapiens
Background Reference 01
Adkins, R.M., et al. Pediatr. Res. 68 (5) :429-434 (2010)
Background Reference 02
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 03
Li, J., et al. Mol. Biol. Rep. (2010) In press :
Background Reference 04
Hsieh, Y.Y., et al. Anticancer Res. 30 (6) :2203-2208 (2010)
Other Product Names
Insulin-like growth factor II, IGF-II, Somatomedin-A, Insulin-like growth factor II, Insulin-like growth factor II Ala-25 Del, Preptin, IGF2
Tested Applications
WB, IHC-P, Flow
Protein ID
124255
Physical Properties
Liquid

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