EGF Antibody

• Background :

  Epidermal growth factor (EGF) has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide. EGF exerts its actions by binding to the EGFR, a 170 kDa protein. Epidermal growth factor is also a key growth factor regulating cell survival. Through its binding to cell surface receptors, EGF activates an extensive network of signal transduction pathways that include activation of the PI3K/AKT, RAS/ERK and JAK/STAT pathways

• NCBI Gene ID :

  25313

• Swiss Prot :

  P07522

• Accession Number :

  P07522

• Host :

  Rabbit

• Reactivity :

  Rat

• Immunogen :

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant Rat EGF (Rat Epidermal Growth Factor) . Rat EGF specific antibody was purified by affinity chromatography employing immobilized Rat EGF matrix.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies, Functional Antibodies, Antibody Pairs

• Field of Research :

  Growth Factors

• Concentration :

  Batch dependent

• Modification :

  None

• Shipping Conditions :

  Room Temp

• Storage Conditions :

  AntiEGF antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol :

  Egf

• NCBI Official Name :

  Epidermal growth factor

• NCBI Organism :

  Rattus norvegicustus norvegicus

• Other Product Names :

  Pro-epidermal growth factorEGF

• Tested Applications :

  ELISA, WB, Neutralization Assay

• Protein ID :

  1352360

• Physical Properties :

  Lyophilized