GPX1 Antibody

• Background:

  GPX1 is an antioxidant enzyme that is down-regulated in cancer cells. Protects the hemoglobin in erythrocytes from oxidative breakdown. Its main role is the prevention of cancer initiation by ROS-mediated DNA damage.

• NCBI Gene ID:

  2876

• Swiss Prot:

  P07203

• Accession Number:

  41406084

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant human GPX1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Concentration:

  1 mg/ml

• Buffer:

  Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Specificity:

  Recognizes human GPX1. Detects a band of ~23kDa by Western blot.

• Applications Notes:

  ELISA: (direct and indirect: 1:2,000-1:5,000) . Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature) . Optimal conditions must be determined individually for each application.

• Symbol:

  GPX1

• NCBI Official Name:

  Glutathione peroxidase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Glutathione Peroxidase 1; GSHPx-1; Cellular Glutathione Peroxidase

• Tested Applications:

  ELISA, WB

• Protein ID:

  NP_000572.2

• Physical Properties:

  Liquid