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ITIH5 Antibody

CAT: 0223-55-530Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-530Size:400 µL
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Background
This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
80760
Swiss Prot
Q86UX2
Accession Number
Q86UX2
Host
Rabbit
Reactivity
Human
Immunogen
This ITIH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 578-606 amino acids from the C-terminal region of human ITIH5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
105 kDa
Fragment
Rabbit Ig
Symbol
ITIH5
NCBI Official Name
Inter-alpha-trypsin inhibitor heavy chain H5
NCBI Organism
Homo sapiens
Background Reference 01
Pita, J.M., et al. Br. J. Cancer 101 (10) :1782-1791 (2009)
Background Reference 02
Veeck, J., et al. Pathologe 29 SUPPL 2, 338-346 (2008) :
Background Reference 03
Veeck, J., et al. Oncogene 27 (6) :865-876 (2008)
Background Reference 04
Hamm, A., et al. BMC Cancer 8, 25 (2008) :
Other Product Names
Inter-alpha-trypsin inhibitor heavy chain H5, ITI heavy chain H5, ITI-HC5, Inter-alpha-inhibitor heavy chain 5, ITIH5, KIAA1953
Tested Applications
WB, IHC-P
Protein ID
187609608
Physical Properties
Liquid

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