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ARHGAP10 Antibody

CAT: 0223-55-349Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-349Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity) .
NCBI Gene ID
79658
Swiss Prot
A1A4S6
Accession Number
A1A4S6
Host
Rabbit
Reactivity
Human
Immunogen
This ARHGAP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-263 amino acids from the Central region of human ARHGAP10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
89 kDa
Fragment
Rabbit Ig
Symbol
ARHGAP10
NCBI Official Name
Rho GTPase-activating protein 10
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Azzato, E.M., et al. Cancer Epidemiol. Biomarkers Prev. 19 (4) :1140-1143 (2010)
Background Reference 03
Lind, P.A., et al. Twin Res Hum Genet 13 (1) :10-29 (2010)
Background Reference 04
Takefuji, M., et al. J. Hum. Genet. 55 (1) :42-49 (2010)
Other Product Names
Rho GTPase-activating protein 10, GTPase regulator associated with focal adhesion kinase 2, Graf-related protein 2, Rho-type GTPase-activating protein 10, ARHGAP10, GRAF2
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid

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