B3GAT2 Antibody

• Background:

  The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system. [provided by RefSeq].

• NCBI Gene ID:

  135152

• Swiss Prot:

  Q9NPZ5

• Accession Number:

  Q9NPZ5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This B3GAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-150 amino acids from the Central region of human B3GAT2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  37 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  B3GAT2

• NCBI Official Name:

  Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care (2010) In press :

• Background Reference 02:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Background Reference 03:

  Shiba, T., et al. Proteins 65 (2) :499-508 (2006)

• Background Reference 04:

  Kakuda, S., et al. Glycobiology 15 (2) :203-210 (2005)

• Other Product Names:

  Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2, Beta-1,3-glucuronyltransferase 2, GlcAT-D, UDP-glucuronosyltransferase S, GlcAT-S, Glucuronosyltransferase S, B3GAT2, GLCATS, KIAA1963

• Tested Applications:

  WB

• Protein ID:

  14285363

• Physical Properties:

  Liquid