ALDH1 Antibody [AHDH1-1]

• Background:

  ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

• NCBI Gene ID:

  216

• Swiss Prot:

  P00352

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A human partial recombinant ALDH1A1 protein (AA 315-434) was used as the immunogen for this ALDH1 antibody.

• Clonality:

  Monoclonal

• Clone:

  AHDH1-1

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1

• Applications Notes:

  1. FFPE testing requires sections to be boiled in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.

• Symbol:

  ALDH1A1

• NCBI Official Name:

  Aldehyde dehydrogenase 1 family, member A1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Retinal dehydrogenase 1, RALDH 1, RalDH1, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, ALDH1A1, ALDC, ALDH1, PUMB1

• Tested Applications:

  WB, Flow, IHC, IF

• Physical Properties:

  Liquid