Transferrin Receptor (Extracellular domain) Antibody [TFRC/1817]

• Background:

  It recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

• NCBI Gene ID:

  7037

• Swiss Prot:

  P02786

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Amino acids 94-212 (extracellular domain) of the human protein were used as the immunogen for the Transferrin Receptor / CD71 antibody.

• Clonality:

  Monoclonal

• Clone:

  TFRC/1817

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Obesity, Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2b, kappa

• Symbol:

  TFRC

• NCBI Official Name:

  Transferrin receptor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, CD71, Transferrin receptor protein 1, serum form, sTfR, TFRC

• Tested Applications:

  Flow, IF, IHC-P, ELISA, WB

• Physical Properties:

  Liquid