Products for Research Use Only

CD31 Antibody [C31.12]

CAT: 0223-33-573Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-33-573Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
NCBI Gene ID
5175
Swiss Prot
P16284
Host
Mouse
Reactivity
Human
Immunogen
Human full length recombinant protein was used as the immunogen for this CD31 antibody.
Clonality
Monoclonal
Clone
C31.12
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1
Symbol
PECAM1
NCBI Official Name
Platelet/endothelial cell adhesion molecule 1
NCBI Organism
Homo sapiens
Other Product Names
Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1
Tested Applications
WB, Flow, IF
Physical Properties
Liquid