CD28 Antibody [204.12]

• Background:

  Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

• NCBI Gene ID:

  920

• Swiss Prot:

  P10747

• Host:

  Mouse

• Reactivity:

  Human, Pig, Bovine, Sheep, Mouse

• Immunogen:

  Stimulated human leukocytes were used as the immunogen for the CD28 antibody.

• Clonality:

  Monoclonal

• Clone:

  204.12

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2a, kappa

• Symbol:

  CD28

• NCBI Official Name:

  CD28 molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CD4 Antibody [9H5A8] : CD4mut

• Tested Applications:

  Flow, IF, Functional Assays

• Physical Properties:

  Liquid