CD7 Antibody [C7/511]

CAT: 0223-33-488Size: 100 µgDry Ice: NoHazardous: No
CAT#:0223-33-488Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
NCBI Gene ID
924
Swiss Prot
P09564
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the CD7 antibody.
Clonality
Monoclonal
Clone
C7/511
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2a
Symbol
CD7
NCBI Official Name
CD7 molecule
NCBI Organism
Homo sapiens
Other Product Names
T-cell antigen CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, CD7, CD7
Tested Applications
WB, Flow, IF
Physical Properties
Liquid

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