CD14 Antibody [LPSR/927]

• Background:

  Recognizes a protein of 55kDa, identified as Cluster of Differentiation 14 (also known lipopolysaccharide receptor or LPSR) . CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. It is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP) . Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

• NCBI Gene ID:

  929

• Swiss Prot:

  P08571

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Human CD14 recombinant protein was used as immunogen for this CD14 antibody.

• Clonality:

  Monoclonal

• Clone:

  LPSR/927

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1, kappa

• Symbol:

  CD14

• NCBI Official Name:

  CD14 molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form, CD14

• Tested Applications:

  WB, Flow, IF

• Physical Properties:

  Liquid