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CD5 Antibody [CRIS-1]

CAT: 0223-33-084Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-33-084Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This antibody recognizes a 67kDa transmembrane protein, which is identified as CD5. It is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in Tcell areas. CD5 antibody is a pan Tcell marker that also reacts with a range of neoplastic Bcells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large Bcell lymphoma. Aberrant expression is useful in making a diagnosis of mature Tcell neoplasms. CD5 antibody detection is diagnostic in CLL/SLL within a panel of other Bcell markers, especially one that includes anti-CD23. CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, it can be used in distinguishing thymic carcinoma (+) from thymoma (-) . It does not react with granulocytes or monocytes.
NCBI Gene ID
921
Swiss Prot
P06127
Host
Mouse
Reactivity
Human, Rhesus Monkey
Immunogen
Stimulated human leukocytes were used as the immunogen for this CD5 antibody.
Clonality
Monoclonal
Clone
CRIS-1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2a, kappa
Symbol
CD5
NCBI Official Name
CD5 molecule
NCBI Organism
Homo sapiens
Other Product Names
T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1
Tested Applications
Functional Assays, Flow, IF
Physical Properties
Liquid

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