GCNT2 Antibody

CAT: 0223-55-091Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-091Size:400 µL
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Background
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
NCBI Gene ID
2651
Swiss Prot
Q06430
Accession Number
Q06430
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-391 amino acids from the C-terminal region of human GCNT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Symbol
GCNT2
NCBI Official Name
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B
NCBI Organism
Homo sapiens
Background Reference 01
Twu, Y.C., et al. Blood 110 (13) :4526-4534 (2007)
Background Reference 02
Wang, L., et al. Biochem. Biophys. Res. Commun. 331 (4) :958-963 (2005)
Background Reference 03
Pras, E., et al. Invest. Ophthalmol. Vis. Sci. 45 (6) :1940-1945 (2004)
Background Reference 04
Inaba, N., et al. Blood 101 (7) :2870-2876 (2003)
Other Product Names
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
Tested Applications
WB, IHC-P
Protein ID
298351849
Physical Properties
Liquid

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