GCNT2 Antibody

• Background :

  This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

• NCBI Gene ID :

  2651

• Swiss Prot :

  Q06430

• Accession Number :

  Q06430

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-391 amino acids from the C-terminal region of human GCNT2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  46 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  GCNT2

• NCBI Official Name :

  N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Twu, Y.C., et al. Blood 110 (13) :4526-4534 (2007)

• Background Reference 02 :

  Wang, L., et al. Biochem. Biophys. Res. Commun. 331 (4) :958-963 (2005)

• Background Reference 03 :

  Pras, E., et al. Invest. Ophthalmol. Vis. Sci. 45 (6) :1940-1945 (2004)

• Background Reference 04 :

  Inaba, N., et al. Blood 101 (7) :2870-2876 (2003)

• Other Product Names :

  N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1

• Tested Applications :

  WB, IHC-P

• Protein ID :

  298351849

• Physical Properties :

  Liquid