Products for Research Use Only
RegisterLogin

SOX2 Antibody

CAT: 0223-31-255Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-31-255Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) . Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
6657
Swiss Prot
P48431
Accession Number
NP_003097
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SOX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
OVCAR-3 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SOX2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
34 kDa
Applications Notes
SOX2 antibody can be used for detection of SOX2 by ELISA at 1:12500. SOX2 antibody can be used for detection of SOX2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SOX2
NCBI Official Name
SRY (sex determining region Y) -box 2
NCBI Organism
Homo sapiens
Background Reference 01
Wang, P., (2008) Arch. Ophthalmol. 126 (5), 709-713 .
Other Product Names
SOX2, ANOP3, MCOPS3, MGC2413
Tested Applications
ELISA, WB
Protein ID
28195386
Physical Properties
Liquid

Related Products

CatalogName
5583PSOX2 Peptide
40-119-0005mgSox2 Recombinant Protein
40-119-01Sox2 Recombinant Protein
40-119-0025mgSox2 Recombinant Protein
40-120-0025mgSox2-TAT Recombinant Protein
40-120-0005mgSox2-TAT Recombinant Protein
40-120-01Sox2-TAT Recombinant Protein
56-211SOX3 Antibody
46-425SOX8 Antibody
28-911SOX3 Antibody

Alternative Products

CatalogName
70R-SR013Sox2 antibody

Popular Products