RELA Antibody

• Background :

  P65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex.

• NCBI Gene ID :

  5970

• Swiss Prot :

  Q04206

• Accession Number :

  NP_068810

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RELA.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription, Cancer, Signal Transduction, Immunology, Apoptosis

• Purification :

  Antibody is purified by Protein A/G affinity chromatography method.

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RELA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  60 kDa

• Applications Notes :

  RELA antibody can be used for detection of RELA by ELISA at 1:62500. RELA antibody can be used for detection of RELA by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  RELA

• NCBI Official Name :

  V-rel avian reticuloendotheliosis viral oncogene homolog A

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ruben, S.M., et al., (1991) Science 251 (5000) 1490-1493..

• Other Product Names :

  RELA, p65, NFKB3

• Tested Applications :

  ELISA, WB

• Protein ID :

  223468676

• Physical Properties :

  Liquid