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CHRND Antibody

CAT: 0223-31-099Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-099Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
NCBI Gene ID
1144
Swiss Prot
Q07001
Accession Number
NP_000742
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRND.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CHRND antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
59 kDa
Applications Notes
CHRND antibody can be used for detection of CHRND by ELISA at 1:312500. CHRND antibody can be used for detection of CHRND by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CHRND
NCBI Official Name
Cholinergic receptor, nicotinic, delta (muscle)
NCBI Organism
Homo sapiens
Background Reference 01
Gomez, C.M., et al., (2002) Ann. Neurol. 51 (1), 102-112.
Other Product Names
CHRND, ACHRD, CMS2A, FCCMS, SCCMS
Tested Applications
ELISA, WB
Protein ID
4557461
Physical Properties
Liquid

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