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CXCL12 Antibody

CAT: 0223-31-056Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-056Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.
NCBI Gene ID
6387
Swiss Prot
P48061
Accession Number
NP_000600
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CXCL12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction, Immunology, Growth Factors
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CXCL12 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
11 kDa
Applications Notes
CXCL12 antibody can be used for detection of CXCL12 by ELISA at 1:62500. CXCL12 antibody can be used for detection of CXCL12 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CXCL12
NCBI Official Name
Chemokine (C-X-C motif) ligand 12
NCBI Organism
Homo sapiens
Background Reference 01
Sadir, R., et al., (2004) J. Biol. Chem. 279 (42), 43854-43860.
Other Product Names
CXCL12, IRH, PBSF, SDF1, TLSF, TPAR1, SCYB12
Tested Applications
ELISA, WB
Protein ID
10834988
Physical Properties
Liquid

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