JPH2 Antibody

CAT: 0223-30-726Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-30-726Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH2 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.
NCBI Gene ID
57158
Swiss Prot
Q9BR39
Accession Number
NP_065166
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human JPH2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store JPH2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
74 kDa
Applications Notes
JPH2 antibody can be used for detection of JPH2 by ELISA at 1:312500. JPH2 antibody can be used for detection of JPH2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
JPH2
NCBI Official Name
Junctophilin 2
NCBI Organism
Homo sapiens
Background Reference 01
Landstrom, A.P., (2007) J. Mol. Cell. Cardiol. 42 (6), 1026-1035.
Other Product Names
JPH2, FLJ40969, JP-2, JP2, CMH17
Tested Applications
ELISA, WB
Protein ID
21704281
Physical Properties
Liquid

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