IGFBP7 Antibody

• Background:

  IGFBP7 contains 1 Ig-like C2-type (immunoglobulin-like) domain, 1 IGFBP N-terminal domain and 1 Kazal-like domain. It binds IGF-I and IGF-II with a relatively low affinity. IGFBP7 stimulates prostacyclin (PGI2) production.

• NCBI Gene ID:

  3490

• Swiss Prot:

  Q16270

• Accession Number:

  NP_001544

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IGFBP7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IGFBP7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  29 kDa

• Applications Notes:

  IGFBP7 antibody can be used for detection of IGFBP7 by ELISA at 1:312500. IGFBP7 antibody can be used for detection of IGFBP7 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  IGFBP7

• NCBI Official Name:

  Insulin-like growth factor binding protein 7

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wajapeyee, N., (2008) Cell 132 (3), 363-374.

• Other Product Names:

  IGFBP7, FSTL2, IGFBP-7, IGFBP-7v, MAC25, PSF, AGM, TAF, IBP-7, RAMSVPS, IGFBPRP1

• Tested Applications:

  ELISA, WB

• Protein ID:

  4504619

• Physical Properties:

  Liquid