SLC7A8 Antibody

• Background:

  SLC7A8 is sodium-independent, high-affinity transport of large neutral amino acids. It has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. SLC7A8 also plays a role in basolateral (re) absorption of neutral amino acids.

• NCBI Gene ID:

  23428

• Swiss Prot:

  A8MTG0

• Accession Number:

  NP_877392

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC7A8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC7A8 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  37 kDa

• Applications Notes:

  SLC7A8 antibody can be used for detection of SLC7A8 by ELISA at 1:312500. SLC7A8 antibody can be used for detection of SLC7A8 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SLC7A8

• NCBI Official Name:

  Solute carrier family 7 (amino acid transporter light chain, L system), member 8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, S. (2005) J. Biol. Chem. 280 (20), 20102-20110.

• Other Product Names:

  SLC7A8, LAT2, LPI-PC1

• Tested Applications:

  ELISA, WB

• Protein ID:

  33286430

• Physical Properties:

  Liquid