Products for Research Use Only
RegisterLogin

IL18RAP Antibody

CAT: 0223-29-706Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-29-706Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
NCBI Gene ID
8807
Swiss Prot
O95256
Accession Number
NP_003844
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL18RAP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction, Immunology
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IL18RAP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
66 kDa
Applications Notes
IL18RAP antibody can be used for detection of IL18RAP by ELISA at 1:312500. IL18RAP antibody can be used for detection of IL18RAP by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IL18RAP
NCBI Official Name
Interleukin 18 receptor accessory protein
NCBI Organism
Homo sapiens
Background Reference 01
Fukushima, K., (2005) J. Biol. Chem. 280 (18), 18056-18062.
Other Product Names
IL18RAP, ACPL, CDw218b, MGC120589, MGC120590, CD218b, IL-1R7, IL18RB, IL-1R-7, IL-18RAcP, IL-1RAcPL, IL-18Rbeta, IL-18R-beta
Tested Applications
ELISA, WB
Protein ID
4504657
Physical Properties
Liquid

Related Products

CatalogName
30-880IL13RA2 Antibody
59-009IL13RA1 Antibody
30-879IL13RA2 Antibody
18-464IL13RA2 Antibody
18-334IL10RA Antibody
22-362IL11RA Antibody
26-140IL11RA Antibody
30-047IL10RA Antibody
63-634IL10RA Antibody
22-228IL18BP Antibody

Alternative Products

CatalogName
MBS8589337-01IL18RAP Antibody

Popular Products