APOBEC3D Antibody

• Background:

  This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA.This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA.

• NCBI Gene ID:

  140564

• Swiss Prot:

  Q96AK3

• Accession Number:

  NP_689639

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APOBEC3D.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store APOBEC3D antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  30 kDa

• Applications Notes:

  APOBEC3D antibody can be used for detection of APOBEC3D by ELISA at 1:62500. APOBEC3D antibody can be used for detection of APOBEC3D by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  APOBEC3D

• NCBI Official Name:

  Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Harris, R.S. (2004) Nat. Rev. Immunol. 4 (11), 868-877.

• Other Product Names:

  APOBEC3D, A3D, ARP6, APOBEC3E, APOBEC3DE

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  187608816

• Physical Properties:

  Liquid