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ZNF496 Antibody

CAT: 0223-29-113Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-113Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn (II) -dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
NCBI Gene ID
84838
Swiss Prot
Q96IT1
Accession Number
NP_116141
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF496.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ZNF496 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
67 kDa
Applications Notes
ZNF496 antibody can be used for detection of ZNF496 by ELISA at 1:62500. ZNF496 antibody can be used for detection of ZNF496 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ZNF496
NCBI Official Name
Zinc finger protein 496
NCBI Organism
Homo sapiens
Background Reference 01
Rual, J.F., (2005) Nature 437 (7062), 1173-1178.
Other Product Names
ZNF496, NIZP1, ZFP496, ZSCAN49, ZKSCAN17
Tested Applications
ELISA, WB
Protein ID
14249386
Physical Properties
Liquid

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