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SOX2 Antibody

CAT: 0223-28-825Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-825Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) .
NCBI Gene ID
6657
Swiss Prot
P48431
Accession Number
NP_003097
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SOX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SOX2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
34 kDa, 26 kDa, 39 kDa, 29 kDa
Applications Notes
SOX2 antibody can be used for detection of SOX2 by ELISA at 1:1562500. SOX2 antibody can be used for detection of SOX2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SOX2
NCBI Official Name
SRY (sex determining region Y) -box 2
NCBI Organism
Homo sapiens
Background Reference 01
Lei, J.X., (2005) Cell Death Differ. 12 (11), 1368-1377.
Other Product Names
SOX2, ANOP3, MGC2413, MCOPS3
Tested Applications
ELISA, WB
Protein ID
28195386
Physical Properties
Liquid

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