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FOXO3 Antibody

CAT: 0223-28-775Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-775Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
NCBI Gene ID
2309
Swiss Prot
O43524
Accession Number
NP_001446
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXO3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Apoptosis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FOXO3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
71 kDa
Applications Notes
FOXO3 antibody can be used for detection of FOXO3 by ELISA at 1:312500. FOXO3 antibody can be used for detection of FOXO3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
FOXO3
NCBI Official Name
Forkhead box O3
NCBI Organism
Homo sapiens
Background Reference 01
Pew, T., (2008) Endocrinology 149 (5), 2637-2645.
Other Product Names
FOXO3, AF6q21, DKFZp781A0677, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, MGC12739, MGC31925
Tested Applications
ELISA, WB
Protein ID
4503739
Physical Properties
Liquid

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