ANXA2 Antibody

• Background :

  ANXA2 encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. ANXA2 has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for ANXA2.

• NCBI Gene ID :

  302

• Swiss Prot :

  Q8TBV2

• Accession Number :

  NP_004030

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ANXA2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. XBL-10410 - Fetal Lung Tissue Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ANXA2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  37 kDa, 39 kDa, 40 kDa

• Applications Notes :

  ANXA2 antibody can be used for detection of ANXA2 by ELISA at 1:312500. ANXA2 antibody can be used for detection of ANXA2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  ANXA2

• NCBI Official Name :

  Annexin A2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Katsunuma, T., et al., (2004) Int. Arch. Allergy Immunol. 134 (1), 29-33.

• Other Product Names :

  ANXA2, P36, ANX2, LIP2, LPC2, CAL1H, LPC2D, ANX2L4, PAP-IV, HEL-S-270

• Tested Applications :

  ELISA, WB

• Protein ID :

  4757756

• Physical Properties :

  Liquid