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DDX48 Antibody

CAT: 0223-28-492Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-492Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DDX48 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.
NCBI Gene ID
9775
Swiss Prot
P38919
Accession Number
NP_055555
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, C. elegans, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDX48.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DDX48 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
45 kDa
Applications Notes
DDX48 antibody can be used for detection of DDX48 by ELISA at 1:312500. DDX48 antibody can be used for detection of DDX48 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
EIF4A3
NCBI Official Name
Eukaryotic translation initiation factor 4A3
NCBI Organism
Homo sapiens
Background Reference 01
Lee, S., et al., (2002) Cancer Lett. 184 (2), 197-206.
Other Product Names
DDX48, DDX48, MUK34, NUK34, NMP265, eIF4AIII
Tested Applications
ELISA, WB
Protein ID
7661920
Physical Properties
Liquid

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