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C19orf6 Antibody

CAT: 0223-28-012Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-28-012Size:100 µL
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Background
Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas
NCBI Gene ID
91304
Swiss Prot
Q4ZIN3-2
Accession Number
NP_219488
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C19orf6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Membrane
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store C19orf6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
46 kDa
Applications Notes
C19orf6 antibody can be used for detection of C19orf6 by ELISA at 1:62500. C19orf6 antibody can be used for detection of C19orf6 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TMEM259
NCBI Official Name
Transmembrane protein 259
NCBI Organism
Homo sapiens
Background Reference 01
Andersson, O., et al., (2002) Brain Res. Gene Expr. Patterns 1 (3-4), 205-212.
Other Product Names
C19ORF6, MBRL, ASBABP1, C19orf6, R32184_3, MEMBRALIN
Tested Applications
ELISA, WB, IHC
Protein ID
15529970
Physical Properties
Liquid

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