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SNAI2 Antibody

CAT: 0223-27-822Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-822Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
6591
Swiss Prot
O43623
Accession Number
NP_003059
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNAI2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SNAI2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
30 kDa
Applications Notes
SNAI2 antibody can be used for detection of SNAI2 by ELISA at 1:312500. SNAI2 antibody can be used for detection of SNAI2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SNAI2
NCBI Official Name
Snail family zinc finger 2
NCBI Organism
Homo sapiens
Background Reference 01
Mittal, M.K., (2008) Biochem. Biophys. Res. Commun. 372 (1), 30-34.
Other Product Names
SNAI2, MGC10182, SLUG, SLUGH1, WS2D, SNAIL2
Tested Applications
ELISA, WB
Protein ID
11276067
Physical Properties
Liquid

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