FOXC1 Antibody

• Background:

  FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.

• NCBI Gene ID:

  2296

• Swiss Prot:

  Q12948

• Accession Number:

  NP_001444

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FOXC1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  57 kDa

• Applications Notes:

  FOXC1 antibody can be used for detection of FOXC1 by ELISA at 1:62500. FOXC1 antibody can be used for detection of FOXC1 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  FOXC1

• NCBI Official Name:

  Forkhead box C1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mortemousque, B., et al., (2004) Arch. Ophthalmol. 122 (10), 1527-1533.

• Other Product Names:

  FOXC1, ARA, IGDA, IHG1, FKHL7, IRID1, RIEG3, FREAC3, FREAC-3

• Tested Applications:

  ELISA, WB

• Protein ID:

  119395716

• Physical Properties:

  Liquid