Transcription Factor A Antibody

• Background:

  The function remains unknown.This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.

• NCBI Gene ID:

  7019

• Swiss Prot:

  Q00059

• Accession Number:

  NP_003192

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human Transcription Factor A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cell Cycle, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store Transcription Factor A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  29 kDa

• Applications Notes:

  Transcription Factor A antibody can be used for detection of Transcription Factor A by ELISA at 1:1562500. Transcription Factor A antibody can be used for detection of Transcription Factor A by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TFAM

• NCBI Official Name:

  Transcription factor A, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Eve A. Roberts, et al., (2007) Molecular Genetics Metabolism.

• Other Product Names:

  Transcription Factor AntibodiesAM, TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3

• Tested Applications:

  ELISA, WB

• Protein ID:

  4507401

• Physical Properties:

  Liquid