PPP2R1A Antibody

PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1A is an alpha isoform of the constant regulatory subunit A.This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

5518

P30153

NP_055040

Human, Mouse, Rat

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPP2R1A.

Unconjugated

Primary Antibodies

Cell Cycle, Cancer, Signal Transduction, Immunology, Apoptosis

Antibody is purified by peptide affinity chromatography method.

293T Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PPP2R1A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

65 kDa

PPP2R1A antibody can be used for detection of PPP2R1A by ELISA at 1:1562500. PPP2R1A antibody can be used for detection of PPP2R1A by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

PPP2R1A

Protein phosphatase 2, regulatory subunit A, alpha

Homo sapiens

Hong, S., (2007) J. Biol. Chem. 282 (16), 12119-12126.

PPP2R1A, MGC786, PR65A, PP2AAALPHA, PP2A-Aalpha

ELISA, WB

21361399