ZNF41 Antibody

• Background:

  ZNF41 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 18 C2H2-type zinc fingers and 1 KRAB domain. ZNF41 may be involved in transcriptional regulation. A chromosomal aberration, translocation t (X;7) (p11.3; q11.21), involving ZNF41 has been found in a patient with sever mental retardation. This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23. Several alternatively spliced transcript variants have been described, however, the full-length nature of only some of them is known.

• NCBI Gene ID:

  7592

• Swiss Prot:

  A8K1V6

• Accession Number:

  NP_700359

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF41.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ZNF41 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  89 kDa

• Applications Notes:

  ZNF41 antibody can be used for detection of ZNF41 by ELISA at 1:312500. ZNF41 antibody can be used for detection of ZNF41 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ZNF41

• NCBI Official Name:

  Zinc finger protein 41

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ross, M.T., (2005) Nature 434 (7031), 325-337.

• Other Product Names:

  ZNF41, MGC8941, MRX89

• Tested Applications:

  ELISA, WB

• Protein ID:

  23510455

• Physical Properties:

  Liquid