FBXW11 Antibody

FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

23291

Q9UKB1

NP_036432

Human, Mouse

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXW11.

Unconjugated

Primary Antibodies

Signal Transduction

Antibody is purified by peptide affinity chromatography method.

721_B Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FBXW11 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

62 kDa

FBXW11 antibody can be used for detection of FBXW11 by ELISA at 1:312500. FBXW11 antibody can be used for detection of FBXW11 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

FBXW11

F-box and WD repeat domain containing 11

Homo sapiens

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007) .

FBXW11, BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696

ELISA, WB

48928050