MS4A2 Antibody

CAT: 0223-23-650Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-23-650Size:100 µL
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Background
The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation.
NCBI Gene ID
2206
Swiss Prot
Q01362
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MS4A2 (NP_000130.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 27kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MS4A2
Positive Control 2
Raji
NCBI Official Name
Membrane spanning 4-domains A2
NCBI Organism
Homo sapiens
Other Product Names
APY, ATOPY, FCER1B, FCERI, IGEL, IGER, IGHER, MS4A1, high affinity immunoglobulin epsilon receptor subunit beta, Fc fragment of IgE, high affinity I, receptor for; beta polypeptide, High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor, beta-subunit) (Fc epsilon receptor I beta-chain), high affinity IgE receptor beta subunit, igE Fc receptor subunit beta, immunoglobulin E receptor, high affinity, beta polypeptide, membrane-spanning 4-domains subfamily A member 2
Tested Applications
WB
Physical Properties
Liquid

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