VPS37A Antibody

• Background:

  This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

• NCBI Gene ID:

  137492

• Swiss Prot:

  Q8NEZ2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_689628.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 44kDa

• Fragment:

  IgG

• Symbol:

  VPS37A

• Positive Control 2:

  Jurkat

• Positive Control 3:

  HepG2

• NCBI Official Name:

  Vacuolar protein sorting 37 homolog A (S. cerevisiae)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  VPS37A, FLJ32642, FLJ42616, HCRP1, PQBP2, SPG53

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid